Today there is large number types of contraception. Oral contraceptives are very popular among other methods. This method is very accessible. In addition to avoiding unwanted pregnancy, they can solve various problems female body.
Modern drugs the most gentle than when they were before. If they are chosen by a specialist, then there will be no health problems. Very often, doctors prescribe two drugs to patients - “Midiana” and “Yarina”, which have the same composition, but there are still differences from each other. This will be discussed later.
Characteristics of the drug "Midiana"
The composition of the contraceptive "Midiana" includes two active ingredients a – this drospirenone And ethinylestradiol.
The effectiveness of this drug lies in the fact that it inhibits the process of ovulation and changes in the endometrium. Due to what it includes in its composition drospirenone, then it has antiandrogenic and slight antimineralocorticoid effects. Drospirenone is very close to natural progesterone.
It has been established that in women who took and are taking combined oral contraceptives, the development of endometrial and ovarian cancer is less common.
The product must be taken daily for 21 days, preferably at the same time. If for any reason a dose is missed, then you must immediately take the missed pill and use other methods of contraception, as there is a possible risk of unplanned pregnancy. After 21 days, a seven-day break is taken, during which the menstrual cycle begins.
Taking Midiana should only be started after consultation and prescription by a gynecologist. Like everyone else / medicines, this drug has contraindications and side effects. But all this can be avoided if you trust a competent specialist.
Description of the oral contraceptive "Yarina"
The composition of the drug "Yarina" includes the active substance: ethinylestradiol And drospirenone.
"Yarina" refers to a contraceptive drug. This is a drug with a low dosage of estrogen and progestogen. Its effectiveness lies in the fact that it helps suppress ovulation and increases the viscosity of cervical mucus. "Yarina" helps prevent unwanted pregnancy.
Women who regularly take this drug suffer less pain during menstrual cycle, the duration and intensity of the cycle is reduced. Women are less likely to suffer from iron deficiency anemia. The risk of endometrial and ovarian cancer is reduced.
Due to the fact that Yarina includes drospirenone, then the risk of weight gain is very low. This component also helps get rid of acne problems and improves hair structure.
The drug must be taken every day for 21 days, then take a seven-day break. Before taking Yarina, you need to consult a specialist.
What do “Midiana” and “Yarina” have in common?
These two drugs have much in common with each other, since the composition of these drugs is the same. These tablets contain the same amount active substances: ethinyl estradiol – 30 mcg, drospirenone – 3 mg.
In addition to their similar composition, they have the same pharmacological action, namely:
- Protects against unwanted pregnancy.
- Help in treatment gynecological diseases, such as: ovarian cyst, hormonal imbalance, etc.
- While taking it, you can forget about problems with acne and acne.
- The menstrual cycle is normalized, there is no pain.
- The structure of hair and skin improves.
In addition to the benefits of these funds, there may be side effects, which are similar. But side effects may not always appear, everything is individual.
Distinctive features of these two drugs
"Midiana" is an analogue of "Yarina". First of all, they differ significantly in price. "Midiana" almost two times cheaper than Yarina. This difference is quite significant, since not everyone can afford a drug that is twice as expensive.
Despite the fact that these two products contain the same components and in equal quantities, they still have several distinctive features.
Here are a few characteristics that distinguish each drug from each other:
The excipients include: differences in the number of components in a drug, for example:
- In Midian the corn starch content is 8 mg., and in “Yarin” - 14.4 mg.
- The content of povidone K25 in the first preparation is – 6 mg., in the second – 4 mg.
- Titanium dioxide in the first product contains - 403 mg., in the second – 556.6 mcg.
There are several substances in Midian that are not in Yarin, these include:
- Polyvinyl alcohol.
- Soy lecithin.
“Yarin” also has components that are missing in its analogue, these are:
- Hypromellose (hydroxypropyl methylcellulose).
- Iron oxide.
Due to this difference in the composition of the components, although they are excipients, there may be different reactions and effects on the body. Therefore, medications should only be taken as prescribed by a specialist and under his supervision. If some tablets are not suitable, then an analogue is prescribed. After all, “Midiana” is best suited for some, and “Yarina” for others. Everything is individual.
Who needs to take Midiana, and who needs Yarina?
These two remedies must be taken by all girls and women who are not planning a pregnancy in the near future, or who have any health problems.
There are no clear distinctions in the use of these remedies, since everything is individual and you can find out which of them is suitable for a particular woman only after use.
It may be that the patient has individual intolerance any components that are part of “Midiana” or “Yarina”, then they usually select another analogue product that does not cause side effects.
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Among the large selection of contraception, many women prefer to use contraceptives, which will help not only protect against unwanted pregnancy, but also with making the right choice medications, regulate hormonal background. The list of such drugs is quite extensive, but doctors in the field of gynecology often recommend that their patients take a drug such as Yarina, which is a combination drug. hormonal drugs with a pronounced and broad mechanism of action. Yarin tablets are quite expensive, so many are looking for cheaper analogues with identical composition and mechanism of action.
The pharmacological market provides a fairly large assortment of structural analogues of Yarin, that is, those that have an identical composition and principle of action, but are produced by other manufacturers and have a lower cost. Despite the widespread use of the drug Yarina and its analogues, it is important to understand that these medications are hormonal, they have many contraindications and side effects, and therefore can only be used as prescribed by a gynecologist and only after a comprehensive gynecological examination.
Brief description of the drug
Yarina is a combined monophasic drug with a pronounced contraceptive effect. The medicine contains two sex hormones - estrogen and gestagen, which have the ability to improve hormonal levels and eliminate the risk of unwanted pregnancy. The principle of action is based on suppressing ovulation, changing the composition of mucus in the cervix. The intake allows you to increase the thickness of the secretion, thereby preventing the penetration of sperm into the uterus. In addition to contraceptive effects, Yarina tablets improve the menstrual cycle, reduce pain during menstruation, and reduce the intensity of uterine bleeding. The drug has a pronounced antiandrogenic effect and regulates the functioning of the sebaceous glands.
Yarina tablets contain ethinyl estradiol (0.03 mg) and drospirenone (3 mg), which are new generation components. The drug is available in tablet form. The blister contains a calendar blister with 21 tablets, which must be used daily. The break between doses takes 7 days - the period of menstruation.
The manufacturer of the contraceptive Yarina recently provided an oral contraceptive - Yarina Plus, which, unlike the brand, in addition to the active components, contains calcium levomefolate, which is a form folic acid. Yarina Plus is intended for women who suffer from folate deficiency.
Yarina Plus, as well as the branded form of the medicine, has many contraindications that you need to familiarize yourself with before taking the medicine. There are quite a few analogues of Yarin, but despite the identical composition, they are produced by different manufacturers who use different cleansing techniques, which can affect the quality of the product and the health of the woman herself. Similar drugs are classified as generics, the prices of which are lower. Generic drugs contain the same components, but different technologies are used in the production process of such drugs. The cost of Yarin tablets is about 950 rubles per pack of 21 tablets.
Jess
Jess is an oral contraceptive with antiadrogenic action. The medicine is a structural analogue of Yarin. Available in blister packs of 28 pieces. The basis is provided by ethinyl estradiol 20 mcg and drospirenone 3 mg, as well as auxiliary components. Taking it allows you to avoid unwanted pregnancy, normalize the menstrual cycle, and eliminate the risk of developing iron deficiency anemia in patients with heavy uterine bleeding. The price of the drug is 650 rubles per blister No. 28.
Indications
The hormonal contraceptive Jess is used for the following conditions:
- Protects against unwanted pregnancy.
- Complex treatment of acne vulgaris with hormonal imbalance.
- Heavy premenstrual syndrome.
The use of the drug allows you to normalize hormonal levels, reduce the risk of developing benign and malignant tumors organs of the reproductive system.
Method of administration
The drug Jess must be used strictly following a special regimen, which is well described in the instructions. The medication is taken from the first day of the menstrual cycle. The blister is designed for 28 days of use. During the onset of menstruation, the medication is stopped for 7 days, after which it is resumed. It is recommended to take the tablets at the same time of day.
Contraindications
Contraindications to the use of the drug are:
- Poor circulation;
- Increased tendency to thrombosis.
- Tendency to thrombosis.
- Varicose veins.
- Heart pathologies.
- Pancreatitis in the acute stage.
- Severe pathologies of the liver and kidneys.
- Age up to 18 years and after 35 years.
Dailla
Dailla - contraceptive hormonal drug based on ethinyl estradiol and drospirenone. It has antiandrogenic, moderate antimineralocorticoid properties, intended for the treatment of hormonal dysfunctions of the female body or as contraceptive. Refers to structural analogues of Yarina. The cost of the drug is about 800 rubles.
Indications
Intended for oral contraception if you do not want to get pregnant.
Method of administration
Dailla tablets are taken orally. The drug is designed for daily use. The dosage regimen is written on the blister with the medicine, as well as in official instructions. Use the drug for 21 days before the onset of menstruation.
The first dose of medication is taken on the first day of menstrual bleeding.
Contraindications
- Severe cardiac pathology: hypertension, angina, risk of stroke or heart attack. Liver failure.
- Cerebrovascular diseases.
- Diabetes mellitus.
- Pancreatitis.
- Hypersensitivity to the composition.
- Bleeding from the vagina of unknown origin.
- Lactation.
- Oncological processes.
Midiana
Midiana is a drug from the group of contraceptives. It has the ability to change the endometrium, inhibit ovulation, and has an antiandrogenic effect. The medicine contains the same components as in Yarin. Available in tablets white in blister No. 21. Clinical trials have shown that taking it not only protects a woman from unwanted pregnancy, but also significantly reduces the risk of developing cancer cells in the ovaries. The price for the generic is approximately 690 rubles per blister No. 21.
Indications
The drug is intended for contraception.
Method of administration
The medicine must be taken at the same time of day and only strictly according to the regimen indicated in the instructions. Therapeutic course is 21 days, then a week off and continuing to take the drug according to the same regimen.
Contraindications
Median has a number of contraindications that you need to familiarize yourself with before taking the medicine. Do not take if there is damage to the valvular apparatus of the heart, arterial hypertension, atrial fibrillation, diabetes mellitus and other conditions described in the instructions.
Dimia
Dimia is a combined monophasic contraceptive intended to prevent unwanted pregnancy. The basis of the medicine is provided by the same drospirenone and ethinyl estradione, which are present in Yarin. The mechanism of action is no different from the branded product, but the price of the drug is much lower. You can buy the medicine in city pharmacies for 680 rubles per pack.
Indications
Dimia tablets are used to prevent unwanted pregnancy in women over 18 years of age.
Method of administration
Take 1 tablet per day. The order of administration is indicated on the blister.
Contraindications
- Individual intolerance.
- Hormone-dependent malignant tumors.
- Thrombosis.
- Angina pectoris.
- Smoking.
- Age up to 18 years and after 35 years.
Having become familiar with the cost of Yarin tablets and analogues, we can conclude that the price difference between the drugs is not significant at all. Therefore, do not try to change one drug for another on your own. Oral contraceptives provide good protection against unwanted pregnancy, but such drugs often cause adverse reactions body, so they can only be prescribed by a gynecologist.
Actually, I don’t use hormonal contraceptives, although these drugs have already been time-tested and many different reviews have been written about them. But my friends have already tried a lot of things, so of course I can tell you something. They mainly take Yarina, Regulon, Jess.
This remedy is considered somewhat similar to yarina, but cheaper. In any case, it costs significantly less in pharmacies.
So, my friend initially took Novinet, but while taking it, complications appeared in the form of intermenstrual bleeding. I had to refuse. Then Regulon and Tri-Mercy were tried, but they also gave undesirable consequences - albeit of a different nature - the body and legs began to swell, even the pants became difficult to fasten, whereas before this contraception they sat almost loosely. In addition, kidney diseases have worsened - cystitis had hardly bothered me before, but now it hit me with renewed vigor. And finally, you can’t hide the weight gain anywhere, it was noticeable even externally from my friend, she became rounder and fuller. Most likely, this was due to the estrogens contained in the tablets, which, due to the specific composition, are to some extent capable of retaining fluid in the body, and thus swelling of the body occurs. In total, the weight gain was about 5.5 kilograms, which is not at all small... And the final nail in the road to taking this drug was allergic reaction in the form of urticaria, which forced me to stop taking these pills.
Yarina or Midiana?
The gynecologist suggested making this choice - both drugs contain ethinylestradiol and drospirenone. The last hormonal component here has an “anti-fluid” effect - it will remove excess water from the body and the body will not swell. Yarina turned out to be a little expensive, so I opted for Midian.
There was a rather long adaptation period to the drug, which made itself felt in full with side effects, which, by the way, they warned about. In particular, the most unpleasant thing was that during the first month I simply got tired of constant bleeding, which, although not particularly strong, still did not stop. From the second month, the bleeding as such stopped and some spotting remained, which persisted until approximately the middle of the menstrual cycle. In the third month there was less smear, a little only in the first week, but only from the fourth month everything finally fell into place, everything began to work clearly. I would like to note, as the gynecologist said, it all depends on individual characteristics body. Some people get used to it almost immediately, for some it will take two months, for others it will take four. Or the drug may not be suitable at all, but this happens relatively rarely.
In addition to the above problems with bleeding, there were headaches, periodic nausea and loss of appetite. Perhaps these were just signs of vegetative-vascular dystonia, but before taking the pills they did not bother me so often, which is why it was concluded that the drug acts on the entire body in a complex and causes a bunch of side effects. These symptoms are likely to worsen during the adaptation period.
But after passing the adaptation period, everything returned to normal, the menstrual cycle returned to normal and began to pass without failures. The periods themselves became less abundant, they became less painful, and premenstrual syndrome itself did not appear as pronounced. sometimes you may not feel it at all. And of course, the drug copes with its contraceptive task very well, there have never been any hints of pregnancy.
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Yarina tablets contain 3 mg and 30 mcg .
Additional substances: titanium dioxide, corn starch, talc, lactose monohydrate, magnesium stearate, hypromellose, macrogol 6000, povidone K25, pregelatinized starch, iron oxide.
Release form
Light yellow tablets with engraving " DO» in a hexagon, 21 tablets in a blister, one or three blisters in a cardboard package.
Pharmacological action
Contraceptive And estrogen-progestogen action.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The abstract describes the drug as a monophasic low-dose oral combined estrogen-progestogen.
Yarina acts by blocking ovulation and increasing the viscosity of cervical mucus.
In women using birth control pills Yarina, the menstrual cycle is normalized, menstrual-like painful bleeding is less frequently detected, the intensity and duration of bleeding is reduced, resulting in a reduced likelihood iron deficiency anemia . There is evidence of a reduced risk of ovarian cancer And .
Contraindications
Contraindications to the use of Yarina tablets:
- current and past and thromboembolism (including , ), cerebrovascular changes;
- current and past hypertriglyceridemia ;
- current and past pre-thrombosis conditions (including, ischemic attacks );
- current and past neurological symptoms;
- with vascular complications;
- risk factors vascular thrombosis , for example, complicated changes in heart valves, vascular diseases brain or heart, surgery followed by long-term immobilization, smoking after 35 years;
- decompensated or acute renal failure;
- insufficiency of liver function or severe liver disease (until normalization of tests);
- current and past liver tumors;
- hormone dependent or suspected of them;
- bleeding from the vagina of unknown origin;
- pregnancy or suspicion of pregnancy;
- hypersensitivity to the components of the drug.
If any of the above disorders develop for the first time while taking the medication, it should be discontinued immediately.
Yarina hormonal tablets should be taken with extreme caution if you have any of the following conditions or diseases:
- risk factors for thrombosis: smoking , arterial hypertension, dyslipoproteinemia , extensive trauma, migraine , prolonged immobilization, heart valve defects, surgical interventions, hereditary predisposition to the development thrombosis ;
- other diseases that can provoke changes in peripheral circulation or superficial phlebitis ;
- hypertriglyceridemia;
- hereditary genesis;
- liver diseases;
- postpartum period;
- diseases that arose or were complicated during pregnancy or previous use of sex hormones ( porphyria , jaundice , pregnant women, cholelithiasis, otosclerosis, Sydenham chorea ).
Side effects
As with taking other combined contraceptives in very rare cases, side effects of Yarina are possible, such as thromboembolism or thrombosis .
Side effects of Yarina:
- from the outside genital area: discharge from the vagina or mammary glands, pain and enlargement of the mammary glands;
- from the outside digestion: vomiting, abdominal pain, nausea, ;
- from the outside vision: discomfort when using contact lenses;
- disorders from nervous activity: worsening mood, mood changes, weakening or strengthening libido , migraine ;
- leather: erythema nodosum , rash, , erythema multiforme ;
- from the metabolic side: weight change, water retention in the body;
- other disorders: .
Instructions for use of Yarina (Method and dosage)
The tablets should be taken orally in order, according to the directions on the package, at the same time every day, with water.
Yarina tablets, instructions for use
The drug is taken 1 tablet per day for 3 weeks. Taking tablets from the next pack should begin after a seven-day break with the usually developing " withdrawal bleeding " It begins approximately 3 days after taking the last tablet and can continue until the use of tablets from a new blister.
Start of reception
How to take Yarina for the first time?
If you have not used any hormonal contraceptives in the previous month, the use of the medicine begins on the 1st day of the menstrual cycle. It is also permissible to start using it on days 2-5 of the menstrual cycle, but in this case you need to use a barrier method of contraception in the 1st week of use.
If the patient switches from other oral combined contraceptives, contraceptive patch or vaginal ring , then it is advisable to start using the medicine on the day following the taking of the last tablet of the “old” drug, but no later than the next day after the standard 7-day break (for products containing 21 tablets) or after taking the final inactive tablet (for products including 28 tablets ). When using a vaginal ring or contraceptive patch, use of the medication should begin on the day the patch or ring is removed, but no later than the day a new ring or patch is installed.
Transition from contraceptives ( containing only gestagen ) to Yarina can be carried out on any day (without a temporary break). Transition from implant containing only gestagen , or a gestagen-releasing intrauterine contraceptive - on the day of its removal. Transition from injection form – from the day on which the following procedure must be performed. In all of the above cases, you need to use a barrier method of contraception in the 1st week of use.
After childbirth or in the second trimester, you should start taking the medicine no earlier than 4 weeks after the birth (provided that the mother is not breastfeeding) or the abortion. If use is started later, you need to use a barrier method of contraception in the 1st week of use. But if the patient has already had sexual intercourse, before starting to use Yarina, it is necessary to exclude pregnancy or wait until the 1st menstruation.
After an abortion in the 1st trimester of pregnancy, it is allowed to start taking the medication on the day of the abortion. If this condition is met, the patient does not need additional methods of contraception.
Missed pills
less than 12 hours late , contraceptive protection is not reduced. A woman needs to take the pill as quickly as possible, the next pill is taken at the usual time.
If the medicine was taken with more than 12 hours late , contraceptive protection is reduced. How more missed pills, the greater the likelihood of pregnancy. If you skip 1 tablet, the chance of getting pregnant is minimal. If you are late for more than 12 hours, follow the recommendations below.
The pass was made in the first 7 days of taking the drug
You should take the last missed tablet as soon as possible, even if you need to take 2 tablets together. The next tablet is taken at the usual time. It is recommended to use a barrier method of contraception for another week. If you had sexual intercourse within 7 days before missing a pill, you must consider the possibility of pregnancy.
The pass was made on days 8-14 of taking the drug
You should take the last missed tablet as soon as possible, even if you need to take 2 tablets together. The next tablet is taken at the usual time. If the patient has taken the pills correctly over the past 7 days, then there is no need to use additional contraceptive measures. IN otherwise or if you miss 2 or more tablets, you must additionally use barrier methods of contraception for another week.
The pass was made on days 15-21 of taking the drug
The risk of pregnancy increases due to the upcoming temporary break in taking the drug. The patient must do one of the following two options. Moreover, if over the last week the pill regimen has been followed, then there is no need to use additional methods contraception.
- You should take the last missed pill as soon as possible, even if this means taking 2 pills at the same time. Subsequent tablets from the current package are consumed as usual until they run out. The next package should be used without interruption. Until the tablets from the second package run out, withdrawal bleeding is unlikely, but breakthrough bleeding and spotting while using the tablets cannot be ruled out.
- You need to stop taking the tablets from the current blister and start a seven-day break, and then start taking the medicine from the new blister. If the patient has violated the regimen of taking the pills and did not develop withdrawal bleeding during the seven-day break, pregnancy must be excluded.
For vomiting and diarrhea
Whenever vomiting or within four hours after taking the tablets, they may not be completely absorbed. In such a case, measures should be taken additional measures contraception, and also need to focus on the above recommendations when skipping pills.
How to change the first day of the menstrual cycle?
To postpone the 1st day of menstruation, you need to continue taking Yarina from a new package without a seven-day break and take the tablets as needed. In this case, it is possible spotting or bleeding.
Overdose
List of symptoms that occur during an overdose: vomit , bleeding from the vagina , nausea .
Overdose therapy is symptomatic. There is no election.
Interaction
The use of drugs that stimulate the functioning of hepatic microsomal cells may cause an increase in the excretion of reproductive organs, which causes breakthrough bleeding or weakening of the reliability of contraception. These medications include , barbiturates, and others.
Arterial thromboembolism can lead to death.
Risk of occurrence thrombosis And thromboembolism increases:
- in smokers;
- with age;
- for obesity;
- if available thromboembolism ever to immediate family or parents;
- with prolonged immobilization, surgical intervention, operations on lower limbs(in these situations, it is advisable to stop the use of combined contraceptives and not resume it for 15 days after completion of immobilization);
- at arterial hypertension ;
- at dyslipoproteinemia ;
- for diseases of the heart valves;
- at migraines ;
- at atrial fibrillation .
Increased frequency and severity of attacks migraines during the period of use of combined contraceptives may be grounds for stopping their use.
The appearance of benign liver tumors has rarely been observed during the use of combined contraceptives, and malignant ones have been observed extremely rarely.
In patients with hypertriglyceridemia it is possible that the likelihood of developing pancreatitis when taking medications like Yarina.
In women with hereditary Quincke's edema exogenous estrogens can cause or worsen the course of this disease.
While taking combined contraceptives, irregular bleeding or spotting may occur, especially during the first months of use. Therefore, assessment of irregular bleeding of any nature should be carried out only after an adaptation period of approximately 3 cycles has been completed.
If the bleeding described above recurs, it is necessary to conduct an examination and examination to exclude malignant tumors or pregnancy.
Simicia.
The price of Yarina's analogues is usually less affordable than the price of the described drug.
Which is better: Midiana or Yarina?
and Yarina are complete analogues by composition and quantitative ratio of components in the preparation. Reviews indicate that there are no fundamental differences in the effect of these two products. Midiana is cheaper in cost. The choice should be made based on economic considerations and individual tolerance.
Which is better: Novinet or Yarina?
and Yarina differ somewhat in their active ingredients, but not in their mechanism of action. The cost of Novinet is almost 2 times cheaper, and in addition to the contraceptive effect, it reduces the risk of developing iron deficiency anemia . The choice is made based on the doctor’s recommendations and economic considerations.
Which is better: Yarina or Regulon?
and Yarina are analogues and only slightly differ in the structure of the active substances. The mechanism of action is identical. Reviews do not record differences in the incidence of side effects. The price of Regulon is approximately 2 times lower than the price of the described medicine.
Which is better: Yarina or Klaira?
unlike Yarina, it has a lower concentration of hormonal components and is recommended to take more mature women. The prices of the drugs are comparable. The choice is based on the recommendations of the attending physician and individual indications.
Diana is 35 or Yarina - which is better?
And Yarina is analogous in terms of mechanism of action and effect. However, it is worth noting that the first has a lower concentration of hormonal components and a higher price. Side effects and therapeutic effect depend on individual characteristics.
Yarina and Yarina Plus
The differences between Yarina are that last drug contains additionally calcium levomefolate , reducing the deficit folate in the body of a woman and fetus in the event of an unplanned pregnancy. The prices of the drugs are comparable.
Janine or Yarina - which is better?
and Yarina are analogue drugs. According to statistics, Yarina demonstrates a greater ability to provoke side effects. The prices of the drugs are almost equal.
For children
Alcohol compatibility
Alcohol is not a contraindication for taking Yarina and does not reduce its contraceptive properties.
During pregnancy and lactation
The medicine is not prescribed for detected pregnancy and lactation.
If pregnancy is detected while using Yarina, the medicine must be discontinued immediately. Studies have not found an increased risk of developmental defects in newborns whose mothers took sex hormones before or during pregnancy. early stages. At the same time, the use of combined contraceptives can reduce the volume breast milk and change its composition, therefore the use of such medications is not recommended until breastfeeding is completed.
Yarina's birth control pills have a special composition, which arouses increased interest in them among gynecologists and their patients. This is a modern, high-quality hormonal contraceptive that does not have many of the side effects of other combined oral contraceptives (COCs). It is produced in Germany by the large company Bayer Pharma.
Effect of the drug
Yarin contains two components for hormonal contraception– ethinyl estradiol (estrogenic) and drospirenone (gestagenic) in low dosages (30 mcg and 3 mg, respectively). The medicine is a monophasic contraceptive, that is, in all tablets of the package the ratio of these active ingredients does not change.
While taking it, the likelihood of pregnancy is the same as when using other low-dose COCs. The number of unplanned pregnancies during a year among 100 women does not exceed 1. If the patient follows all the rules for using the drug, the probability of conception approaches 1:500.
Yarina hormonal tablets prevent pregnancy by a combination of the following effects:
- suppression;
- increased mucus viscosity cervical canal, which makes it difficult for sperm to enter the uterus;
- inhibition of cyclic processes occurring during the cycle in the endometrium; in this case, conditions are created that are unfavorable for the implantation of the egg, even if fertilization has occurred.
Thus, the drug affects many processes necessary for conception, so it effectively prevents pregnancy.
Additional medicinal effects:
- restoration of regular menstruation;
- decrease ;
- reducing the amount of blood lost during menstrual or intermenstrual bleeding;
- prevention of iron deficiency anemia in women;
- reducing the risk of ovarian and uterine cancer.
Features and indications
There is nothing unusual about Yarina’s estrogenic component, ethinyl estradiol. It is necessary to regulate the functioning of the ovaries. Its presence in the drug causes some typical side effects of COCs, for example, a tendency to vein thrombosis.
The peculiarity of the product is its gestagen component. Drospirenone, unlike levonorgestrel and other similar substances, has additional activity:
- has an effect similar to medicine spironolactone; that is, it is a weak diuretic that preserves potassium in the body, but at the same time prevents the appearance of edema and other signs;
- does not cause weight gain with long-term use;
- has an antiandrogenic effect: prevents or treats acne, excess oily skin and hair, hirsutism (appearance of facial hair).
These features determine the group of patients for whom Yarina is most suitable. They have the following symptoms:
- swelling, irritability, migraine and other signs of premenstrual syndrome;
- phenomena of hirsutism - acne, excess oiliness of hair and skin, the appearance of unwanted hairs on the face, seborrhea.
Indications for taking Yarina are a necessity. It can be prescribed even to young girls who have started their menstrual cycle, without changing the dose or regimen. After menopause, when there are no cycles, there is no need to use Yarina.
How to drink Yarina?
To simulate the natural menstrual cycle, the drug is taken 21 days in a row, 1 tablet. It is advisable to do this at the same time of day, regardless of meals. After 3 weeks of use, a break of 7 days is required.
On what day do menstruation begin when taking Yarin?
Menstruation begins after 2-3 days. Even if they did not stop by the end of the week's break, they begin the 3-week course again. In this case, it is not necessary to open a new package, since the hormone content in all tablets is the same. However, it is more convenient to start using the drug from the next package, so as not to get confused and prevent missing tablets.
If your period does not end within 2 days after resuming the course of pills, you should consult a doctor.
Effect on the menstrual cycle
In the first months of using the drug, some women experience irregular bleeding. Adaptation occurs within 3 months of use. If after this the regular cycle has not been restored, you need to contact a gynecologist.
It is especially important to consult a doctor in time if, after several normal cycles, irregular discharge appears again. In such a situation, it is necessary to exclude pregnancy and malignant tumors of the genital organs.
Pregnancy after Yarina can occur in the next cycle after the next menstruation.
Start of reception
The doctor who prescribed it should tell you how to take Yarina for the first time. There are also detailed instructions in the instructions for use.
You can end your appointment at any time. If pregnancy is not planned, you should start using others.
Missing an appointment
If the patient forgets to take a pill, resuming use of the medicine depends on how much time has passed since the required but missed dose.
The rules for resuming contraception are determined by the week in which the unplanned break occurred.
1st week
- Take the pill as early as possible. If the patient forgot to use the drug on the previous day, then she will need to take 2 tablets at once (“forgotten” and the next one).
- Take subsequent tablets as usual.
- For a week after this, you must use condoms during sexual intercourse.
- It must be taken into account that pregnancy can also occur if sexual intercourse took place during the previous week before missing the pill.
2nd week
- The basic rules are the same as for skipping the 1st week.
- If the patient took the drug correctly for a week before the unplanned break, additional contraception is not needed.
- If during the week before skipping the drug was taken in violation of the regimen, or if more than one tablet was missed, you must resume your usual daily intake and use condoms over the next week.
3rd week
At this time, the likelihood of an unplanned pregnancy increases. However, if there were no violations in the dosage regimen during the week before skipping, additional contraception is not needed. Otherwise, the patient chooses one of two options:
- Start taking the medication as soon as possible, one tablet per day. In this case, do not take a break between packages. In this case, menstruation will not occur. There may only be a slight spotting discharge. After completing the next pack, take the usual one-week break.
- Do not take pills for a week, including the “missed” day. This will cause menstruation. After 7 days, start using the medicine from a new package. If you don’t have your period after stopping Yarina, you should consult a doctor; you may be pregnant.
Vomiting or diarrhea in the first 4 hours after taking the pill is considered to be missed. In this case, you need to follow the above rules depending on the week in which this happened.
Changing the start date of menstruation
With the help of the drug, you can shift the onset of your next period. This property can be used in exceptional cases, for example, when traveling to the seaside or before an important sports performance.
- To prevent menstruation from starting this month, Yarina should not be discontinued after taking the entire package. Immediately, without a week's break, the medication from the next package begins. It can be continued required quantity days, up to 21. Menstruation will begin 1-2 days after finishing using the medicine. In addition, spotting or short-term menstrual-like bleeding are possible while using the second package. The contraceptive effect is not reduced.
- To reschedule your period a few days earlier, you should reduce the interval between packs by the required number of days in advance. After completing the second package, menstruation will begin, that is, menstruation will come as many days earlier as the “free” interval between packages was shorter.
Side effects
6 out of 100 women taking Yarina experience nausea. With the same frequency, patients have chest pain. If such symptoms appear, you should consult a doctor. You may need to select a different contraceptive.
The most dangerous side effects are thrombosis, that is, blockage of arteries or veins.
In 1-10% of cases the following side effects are observed:
- unstable mood, depression, weakened libido;
- migraine headache;
- irregular bleeding from the vagina.
The development of thrombosis occurs in one in 10,000 women and less frequently. In this case, the following pathological conditions may appear:
- thrombosis of the veins of the extremities;
- pulmonary embolism;
- myocardial infarction;
- ischemic stroke.
In large studies and in practice, conditions have been identified that may be somehow related to taking Yarina, but occur extremely rarely when using this drug:
- slight increase in risk (for patients over 40 years of age);
- increased likelihood of benign or malignant liver tumors;
- the appearance of erythema nodosum - rounded nodes, usually located on the anterior surfaces of the legs;
- pancreatitis with simultaneous increased content triglycerides in the blood;
- arterial hypertension;
- increased symptoms with hereditary angioedema;
- liver dysfunction;
- worsening diabetes;
- ulcerative colitis and Crohn's disease (intestinal damage);
- chloasma (dark spots on the skin);
- manifestations of intolerance, for example, allergic skin rash.
No negative effects on the fetus were detected during early pregnancy. However, if this condition is suspected, the medication should be stopped.
Contraindications
The drug Yarina has the following contraindications:
- previous vascular thrombosis, including deep vein thrombosis, pulmonary embolism, myocardial infarction, ischemic stroke;
- previous transient ischemic attack;
- IHD, including angina pectoris;
- migraine with the appearance of focal neurological symptoms (impaired movements, sensitivity, smell, speech, etc.);
- diabetes complicated by micro- or macroangiopathy (vascular damage);
- factors that increase the risk of vascular thrombosis: atrial fibrillation, valvular heart defects, high blood pressure, transferred surgery with prolonged bed rest or limb immobility, as well as smoking in women over 35 years of age;
- pancreatitis, accompanied by an increase in triglyceride levels in the blood;
- liver diseases with altered liver tests (ALT, AST, alkaline phosphatase, bilirubin);
- liver tumors;
- liver or kidney failure;
- malignant tumor of the genital organs or mammary gland, or suspicion of them;
- vaginal bleeding of unknown origin;
- suspicion of pregnancy;
- breast-feeding;
- individual intolerance.
If the listed conditions appear while taking Yarina, it should be stopped immediately.
This COC can be taken for fibroids, endometriosis, ovarian cysts and other non-tumor diseases of the genital organs.
Interaction with other drugs
Some medications may reduce the contraceptive effectiveness of the drug.
- phenytoin;
- drugs from the group of barbiturates;
- carbamazepine, oxcarbazepine;
- rifampicin and rifabutin;
- topiramate or felbamate;
- griseofulvin;
- products based on St. John's wort;
- some medications for the treatment of HIV infection.
Special rules must be observed when taking antibiotics such as penicillins (Amoxiclav, Oxacillin, Ampicillin and others) and tetracyclines (Doxycycline and others). During treatment with these drugs, as well as for a week after completing the course, you must additionally use condoms.
If during this week, when additional barrier contraception is needed, the pills from the package run out, immediately start the next one, without the usual one-week break.
Yarina and other hormonal contraceptives
The Bayer company, in addition to this drug, produces a similar one - Yarina Plus.
What is the difference between Yarina and Yarina plus?
Yarina plus contains another component - calcium levomefolate, which is active form folic acid. Its purpose is to reduce the risk of defects nervous system fetus, if pregnancy occurs while taking COCs.
This medicine is prescribed to patients who receive insufficient amounts of folic acid.
Which is better: Yarina or other COCs (Jess, Janine, Klaira, Regulon, Belara)?
It is better to get the answer from the gynecologist who is observing you, since all these drugs have differences in properties and are prescribed in different clinical situations:
Complete analogues in composition, cheaper than Yarina:
- Anabella (Czech Republic) - 1400 rubles for 84 tablets;
- Midiana (Hungary) – 740 rubles for 21 tablets;
- Vidora (Spain) – 625 rubles for 21 tablets;
- Modell Pro (Israel) – 691 rubles for 21 tablets;
- Yamera (India).
Preparations Jess and Dimia are practically no different from Yarina, except for the amount of ethinyl estradiol in them - not 30, but 20 mcg.
Yarina is a fairly expensive drug, so you need to ensure its authenticity. To do this, you should take a good look at the tablets from the package. It may contain 1 or 3 blisters of 21 tablets. Each of them has an even light yellow color and is covered with a film shell. On one of the sides there is a hexagon embossed, in which the letters DO are located. You should not take the drug if it external characteristics do not correspond to those indicated, and also if it was sold at a price significantly lower than the average (about 1000 rubles for 21 tablets).